盖微微，女，汉族，1987年3月出生，中共党员

吉林舒兰市人，博士，讲师

研究领域：人兽共患病疫苗；纳米药物递送

电子邮件：377827506@qq.com

主讲课程：微生物的世界（本科）

学习经历

2007-09至2011-07, 在吉林农业大学动物科学与技术学院动物医学专业学习, 获农学学士学位

2011-09至2014-07, 在吉林农业大学动物科学与技术学院攻读预防兽医学硕士研究生, 获农学硕士学位

2014-09至2018-07, 在吉林大学动物医学学院攻读预防兽医学博士研究生，获农学博士学位。

主持课题

1. 内蒙古自治区自然科学基金项目，项目编号：2021BS08023，免疫调节性靶向载药纳米粒的制备及其抗肿瘤研究，2021/01-2023/12，6万元，在研，主持。

2. 内蒙古自治区高等学校科学研究项目，项目编号，NJZZ21030，牛布鲁氏菌S19株细菌样颗粒的制备及免疫原性研究，2021/01-2023/ 12，6万元，在研，主持。

科研论文（近五年）

[1]. Gai Weiwei#; Hao Xuefang#; Zhao Jiadi; Wang Lina; Liu Jinghai; Jiang Haixia;Jin Hua; Liu Guoli;FengYakai; Delivery of benzoylaconitine using biodegradable nanoparticles to suppress inflammation via regulating NF-κB signaling,Colloids and Surfaces B:Biointerfaces, 2020 Jul,191:110980.

[2]. Gai Weiwei#; Zheng Wenwen#; Zhao Zhongxin#; Wong  Gary; Sun Peilu;YanLina;HeHongbin;ZhengXuexing; Assemblyof pigeon circovirus-like particles using baculovirus expression system,Microbial Pathogenesis,2020 Feb,139:103905.

[3]. Hao Xuefang#;GaiWeiwei#;Wang Lina;Zhao Jiadi; Sun Dandan;Yang Fan;Jiang Haixia; Feng Yakai;5-Boronopicolinic acid-functionalized polymeric nanoparticles for targeting drug delivery and enhanced tumor therapy,Materials Science & Engineering C,2021 Feb,119:111553.

[4]. Xuefang Hao#; Weiwei Gai#; Feng ji; Lina Wang; Jiadi Zhao; Fang Yang; Haixia Jiang; Yakai Feng ; Biomimetic and responsive nanoparticles loading JQ1 for dual-targeting treatment of vascular restenosis via multiple actions, Chemical Engineering Journal , 2021, 431(4): 133452.

[5]. Xuefang Hao#; Weiwei Gai#; Feng Ji; Jiadi Zhao; Dandan Sun; Fan Yang; Haixia Jiang; Yakai Feng ; Bovine serum albumin-based biomimetic gene complexes with specificity facilitate rapid re-endothelialization for anti-restenosis, Acta Biomaterialia , 2022 Apr 1;142:221-241. 6.

[6]. Gai W*, Zheng X*, Wang C*, Wang H, Zhao Y,et al. (2017)Marburg virus-like particles by co-expression of glycoprotein and matrix protein induces immune responses in mice. Virology Journal. 2017 Oct 25;14(1):204.

[7]. Gai W*, Zheng X*, Wang C*, Zhao Y, Wang Q, et al. (2017) Marburg virus-like particles produced in insect cells induce neutralizing antibodies in rhesus macaques. Journal of Medical Virology. 2017 Dec;89(12):2069-2074.

[8]. Gai W*, Zheng W*, Wang C*, Wong G, Song Y, et al. Immunization with

recombinant rabies virus expressing Interleukin-18 exhibits enhanced immunogenicity and protection in mice. Oncotarget.2017, Vol. 8, (No. 53), pp: 91505-91515.

[9]. Wang C*, Zheng X*, Gai W*, Zhao Y, Wang H, et al. (2017) MERS-CoV

virus-like particles produced in insect cells induce specific humoural and cellular imminity in rhesus macaques. Oncotarget.2017, Vol. 8, (No. 8), pp: 12686-12694.

[10]. Wang C*, Zheng X*, Gai W*, Wong G, Wang H, et al. (2017) Novel chimeric virus-like particles vaccine displaying MERS-CoV receptor-binding domain

induce specific humoral and cellular immune response in mice. Antiviral Research.2017 Apr;140:140:55-61.

专利

1. 基于蛋白和血小板膜修饰的基因递送系统制备方法和应用，发明人：郝雪芳，盖微微；专利号：ZL202011403571.1，发明专利。

2.一种多功能高效药物递送系统及其制备方法和应用，发明人，郝雪芳，盖微微；专利号：202011606510.5，发明专利。

3. 一种5-硼吡啶羧酸修饰的靶向药物递送系统及其制备方法，发明人，郝雪芳，盖微微；专利号：202010570574.8，发明专利。