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邓清华


图片1.png邓清华,女,汉族,1985年10月出生,中共党员,山东省

烟台市人,博士,副教授。

研究领域:家畜营养代谢病;

电子邮件:18747500536@126.com;电话:18747500536;

主讲课程:家畜内科学;实验动物学;细胞生物学


学习经历

2004.09——2007.07,在吉林农业科技学院动物医学系学习,获得农学学士学位。

2009.09——2012.06,在吉林大学畜牧兽医学院临床兽医学方向攻读硕士研究生,获得农学硕士学位。

2012.09——2015.06,在吉林大学畜牧兽医学院临床兽医学方向方向攻读博士研究生,获得农学博士学位。


主持课题

1.国家自然科学基金委员会,31602121,FMO3调控奶牛内质网应激及脂代谢的作用机制,2017/01-2019/12,24万元,结题,主持

2.青年科技英才项目,NJYT-20-B30,奶牛肝脏的蛋白组学研究,2020/01-2022/12,20万元,在研,主持。

3.内蒙古自治区肉牛疾病防控工程技术研究中心开放课题基金,MDK2019023,肉牛脂肪肝病的肝脂代谢机制及其对炎性通路的影响,2019/07-2021/06,3万元,结题,子课题主持。


科研获奖

1.2015年获吉林省自然学术成果奖二等奖一项。


科研论文

1.Qinghua Deng, Dehui Ma, Guoquan Sun, Xue Yuan, Zhe Wang and Guowen Liu: PTEN influences insulin and lipid metabolism in bovine hepatocytes in vitro. Journal of Dairy Research. 2019; 86(1): 73 – 76.

2.Qinghua Deng, Xinwei Li, Shixin Fu, Liheng Yin, Yuming Zhang, Tingting Wang, Jianguo Wang, Lei Liu, Xue Yuan, Guoquan Sun, Zhe Wang, Guowen Liu and Xiaobing Li: SREBP-1c gene silencing can decrease lipid deposits in bovine hepatocytes cultured in vitro. Cellular Physiology and Biochemistry. 2014; 33: 1568 – 1578.

3.Qinghua Deng, Guowen Liu, Lei Liu, Yuming Zhang, Liheng Yin, Xiaoxia Shi, Jianguo Wang, Xue Yuan, Guoquan Sun, Yu Li, Wei Yang, Lihui Guo, Renhe Zhang, ZheWang, Xiaobing Li, Xinwei Li: BHBA influences bovine hepatic lipid metabolism via AMPK signaling pathway. Journal of Cellular Biochemistry. 2015; 116(6): 1070-1079. 

4.Qinghua Deng, Xiliang Du, Lin Lei, Xiaoyan Zhu, Wenwen Gao, Min Zhang, Xue Yuan, Guoquan Sun, Xiaobing Li, Zhe Wang, Guowen Liu, Xinwei Li: Effects of β-hydroxybutyricacid on the synthesis and assembly of very low density lipoprotein in bovine hepatocytes in vitro. Journal of Animal Physiology and Animal Nutrition. 2016; 100(2): 331-336.

5.Xinwei Li, Yuan Guan, Ying Li, Dianjun Wu, Lei Liu, Qinghua Deng*, Xiaobing Li*, Zhe Wang*, Guowen Liu*. Effects of insulin-like growth factor-1 on the assembly and secretion of very low-density lipoprotein in cow hepatocytes in vitro. General and Comparative Endocrinology. 2016; 226: 82-87.

6.Shi X, Li D, Deng Q, Li Y, Sun G, Yuan X, Song Y, Wang Z, Li X, Li X, Liu G. NEFAs activate the oxidative stress-mediated NF-κB signaling pathway to induce inflammatory response in calf hepatocytes. J Steroid Biochem Mol Biol. 2015 Jan;145:103-12.

7.Liheng Yin, Xia Qin, Qinghua Deng, Yuming Zhang, Lin Lei, Wenwen Gao, Xiliang Du, Guowen Liu, Xinwei Li: The isolation of pre-adipocytes from dairy cow adipose tissue and the development of pre- adipocytes into mature adipocytes. Pakistan Veterinary Journal.

8.Shi X, Li X, Li D, Li Y, Song Y, Deng Q, Wang J, Zhang Y, Ding H, Yin L, Zhang Y, Wang Z, Li X, Liu G: β-Hydroxybutyrate activates the NF-κB signaling pathway to promote the expression of pro-inflammatory factors in calf hepatocytes. Cellular Physiology and Biochemistry. 2014; 33(4):920-32.

9.Li X, Li Y, Yang W, Xiao C, Fu S, Deng Q, Ding H, Wang Z, Liu G, Li X: SREBP-1c overexpression induces triglycerides accumulation through increasing lipid synthesis and decreasing lipid oxidation and VLDL assembly in bovine hepatocytes. J Steroid Biochem Mol Biol. 2014 Sep; 143:174-82.

10.Chen H, Zhang L, Li X, Li X, Sun G, Yuan X, Lei L, Liu J, Yin L, Deng Q, Wang J, Liu Z, Yang W, Wang Z, Zhang H, Liu G: Adiponectin activates the AMPK signaling pathway to regulate lipid metabolism in bovine hepatocytes. J Steroid Biochem Mol Biol. 2013 Nov; 138: 445-54.

11.Fu S, Deng Q, Yang W, Ding H, Wang X, Li P, Li X, Wang Z, Li X, Liu G. Increase of fatty acid oxidation and VLDL assembly and secretion overexpression of PTEN in cultured hepatocytes of newborn calf. Cellular physiology and biochemistry. 2012; 30(4):1005-13.

12.Li X, Li X, Bai G, Chen H, Deng Q, Liu Z, Zhang L, Liu G, Wang Z: Effects of non-esterified fatty acids on the gluconeogenesis in bovine hepatocytes. Mol Cell Biochem. 2012 Jan; 359(1-2): 385-8.

13.Wang J, Zhu X, Li X, Wang W, Wang X, Liu L, Deng Q, Bai G, Wang J, Feng H, Wang Z, Liu G: Effects of copper on proliferation and autocrine secretion of insulin-like growth factor-1 (IGF-1) and IGF-binding protein-3 (IGFBP-3) in chondrocytes from newborn pigs in vitro. Biol Trace Elem Res. 2011 Dec; 144(1-3): 588-96.

14.邓清华刘国文付世新刘磊王晓旭朱晓岩王建国白鸽王振全李小兵王哲:RNAi及沉默通路调控研究进展。中国畜牧兽医[J],2011,38(1):92-95.

15.邓清华付世新刘国文刘磊王建国白鸽朱晓岩李慧萍李小兵王哲: siRNA特异性抑制犊牛原代肝细胞SREBP-1c基因的表达。中国兽医学报[J],2011,31(7):1050-1058.


其他情况

第十一届内蒙古民族大学“科尔沁学者”,2016年获“青年科技创新标兵奖”;2016年获“引进人才科技立项奖”。